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Director, Oligonucleotide Chemistry & Formulations -RNA, Gene Therapy & Delivery | Directo1

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Director, Oligonucleotide Chemistry & Formulations -RNA, Gene Therapy & Delivery

Location:
San Diego, CA
Description:

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Director, Oligonucleotide Chemistry & Formulations in the RNA, Gene Therapy & Delivery organization located in La Jolla, CA. At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at . RNA, Gene Therapy & Delivery is an organization within Therapeutics Discovery, committed to the delivery of high-quality drug candidates in the novel synthetic modalities space working closely with Janssen Therapeutic Areas (TA) discovery teams. Our mission requires critical thinking, a portfolio approach and deep scientific expertise in several fields including oligonucleotide chemistry, bioconjugation chemistry, nanotechnology, cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners. This role offers tremendous growth opportunity within a dynamic and science driven organization. Key Responsibilities: Drive the scientific direction, strategy and provide leadership for the design and synthesis of oligonucleotides and bioconjugates for delivery. Lead efforts in establishing LNP formulation capabilities for RNA therapeutics (oligonucleotides, mRNA, etc.). Lead innovation, optimization, and process development efforts for oligonucleotide therapeutics and LNP formulations. Co-lead and mentor project teams to develop and implement oligonucleotide drug discovery strategies to advance projects through the preclinical stage gates. Work collaboratively with partners in molecular and cellular biology, pharmacology, computational chemistry, ADME, structural biology, chemical development, and other key functions. Build and lead a group of scientists to establish and optimize chemistry processes for solid phase synthesis, purification, analysis of oligonucleotides and bioconjugates. Participate and contribute to discussions and projects with strategic external partners. Manage external CROs and CMOs for to support oligonucleotide synthesis. Critically evaluate experiment data and communicate scientific findings as verbal presentations and written reports, and provide updates on project status to Therapeutics Discovery leadership Team.
Company:
Disability Solutions
May 10 on TopUSAJobs
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Director, Oligonucleotide Chemistry & Formulations -RNA, Gene Therapy & Delivery is a Nurse & Healthcare Director Job at Disability Solutions located in San Diego CA. Find other listings like Director, Oligonucleotide Chemistry & Formulations -RNA, Gene Therapy & Delivery by searching Oodle for Nurse & Healthcare Director Jobs.